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22.7%, 30.2%), and 10% (14.3%, 26.7% vs 3.3%, 7.7%).The SUSTAIN 8 trial [173] (ClinicalTrials.gov identifier: NCT03136484) was a 52- week, double-blind, parallel-group, randomised controlled trial of once-weekly subcutaneous semaglutide 1.0 mg versus oral canagliflozin 300 mg in patients with type 2 diabetes

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Testosterone acts through androgen receptors in osteoblasts, while IGF-1 stimulates osteoblast proliferation and bone matrix synthesis (9)

The trial was designed and sponsored by Novo Nordisk, makers of Ozempic, Wegovy and Rybelsus