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In particular GLP-2 is important for overall gut health, so if you lower natural GLP-1 production you also make your gut less healthy

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Section Summary: You can support ovulation naturally by taking targeted fertility supplements (folic acid, zinc, vitamin D, CoQ10), eating antioxidant-rich foods to protect egg quality, getting 30 minutes of daily moderate exercise to improve blood flow and hormonal balance, maintaining adequate iron levels for healthy follicular development, and eliminating alcohol and drugs that disrupt the hormonal signals controlling ovulation

New England Journal of Medicine , 382(13), 1244-1256

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Cartilage has no blood vessels or nerves, and its cells divide very slowly, leaving it unable to heal itself on its own