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On the other hand, biopsies of those with normal aminotransferase values have revealed bridging fibrosis or cirrhosis in 1% to 10% of cases, and at least portal fibrosis in a greater proportion (see Liver Biopsy section)42, 51, 52, 77

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3 Dependence on clinical suspicion or isolated liver enzyme abnormalities alone is insufficient and contributes to delayed diagnosis

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