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In these models, oral delivery is not a compromiseit is the entire point of the experiment

As obesity drug development expands beyond injectable GLP-1s, companies are advancing oral pills, dual and triple agonists, amylin-based candidates and metabolic disease programs

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In neuronal cell culture models, sulforaphane consistently demonstrates neuroprotection as low as 0.01 M (Vauzour et al., 2010)

Open study with DSIP in patients with insomnia older study In another study (open-label), DSIP was administered to patients with severe insomnia sleep improved for most participants, and mental state and daytime functions were enhanced