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Different EMT marker genes, including several matrix metalloproteinases, were validated by RT-qPCR with MMP1 (matrix metalloproteinase 1), MMP3 (matrix metalloproteinase 3), and CYR61 (cysteine-rich angiogenic inducer 61) being the highest upregulated genes (Figure 13B)

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Compared to patients treated with sodium-dependent glucose transporters 2 (SGLT2) inhibitors as monotherapy, those receiving GLP-1RAs for type 2 diabetes exhibited a significantly increased risk of thyroid hyperplasia and thyroid cancer [22]

"Gastrointestinal Hormones"