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Yeh CW, Tseng LH, Yang CH, Hwang CF

Those considering B12 injections for non-medical purposes should discuss the risk-benefit profile with a healthcare professional, as the potential harms may outweigh any perceived advantages in the absence of deficiency

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doi: 10.1371/journal.pone.0103490

Subsequent peer-reviewed preclinical studies have examined its use as a tool compound for investigating NNMT enzyme activity in adipose, liver, and skeletal muscle cell-based research models under controlled laboratory conditions