5.2.4 Ferroptosis suppressor protein 1 and coenzyme Q10 pathway FSP1 possesses NAD(P)H oxidoreductase activity and reduces CoQ to ubiquinol (CoQH2), which inhibits lipid peroxidation and ferroptosis by trapping lipid peroxidation free radicals (77, 78)
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Studies reporting GSH levels in different blood components (plasma, serum, blood cells) were analyzed as sub-studies, with a total of 33 studies/sub-studies used for AD blood GSH analysis and 8 studies/sub-studies used for MCI blood GSH analysis
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Genetics, hormone levels, age, and even brain chemistry play a role