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There is no single right answer only a risk-benefit calculus that each person should discuss with their prescriber

Patients tapering should start the resistance program before the taper begins, not after, so the metabolic protection is in place before appetite rebounds

However, inhibition of apoC-III synthesis using antisense oligonucleotides (ASO) in mice did not reduce VLDL secretion [13], so the biological significance of apoC-III as a regulator of hepatic VLDL assembly and release is still unclear, particularly in humans

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10.1097/01.MP.0000071842.83169.5A 9

PubMed, Stead, Lori M., et al