The Incretin Concept: From Gut to Glory The story begins with the incretin effectthe observation that glucose taken by mouth triggers a much stronger insulin response by increasing the production of hormones in the pancreas, compared to when it is injected directly into a vein
These powerful weight loss and Type 2 diabetes medications are all GLP-1 drugs
Mild diarrhea or itching
PubMed, doi:10.1016/j.tjog.2013.04.016
(PubMed) Kozlov AV, Gille L, Staniek K, Nohl H
Macroscopic Assessment The depth of destruction in articular cartilage was evaluated according to the measures described by Pelletier et al 32 using a four-point scale (0 = normal-appearing surface, 1 = negligible fibrillation or a minor yellowish discoloration of the surface, 2 = destruction spread out into the superficial or central layers only, 3 = destruction that spread into the deep layers, and 4 = destruction that spread to the subchondral bone)