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[21] The underlying principle, supported by guidelines from the Endocrine Society, American Association of Clinical Endocrinology, and American Gastroenterological Association, is that obesity is a chronic metabolic disease requiring ongoing medical management

A second group of innate lymphoid cells (ILC2s) has a key role in type II immune response

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Furthermore, chronic inflammatory processes, and specifically the concentration of TNF-, drive cardiovascular events, such as atherosclerosis, atherothrombotic disease, and venous thromboembolism [27]

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