PlexusDx offers an alternative pathway: compounded GLP-1 medications manufactured in licensed 503A US pharmacies, available to Canadian residents without insurance requirements or membership fees
There were no differences in older patients with or without comorbidities in either the LixiLan-O or LixiLan-L trials, except for slightly greater weight loss in patients with versus without comorbidities in the LixiLan-O trial (data on file)
Keep a symptom diary noting bowel frequency, consistency (using the NHS Bristol Stool Chart as reference), associated symptoms, and dietary intake
The simplest way to understand the difference is this: tirzepatide is a dual agonist, while retatrutide is a triple agonist
While timing relative to meals is not required by the SmPC, some patients find adjusting the timing helps with tolerability
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