Managing Stress Chronic stress can: Increase emotional eating Worsen blood sugar control Disrupt sleep Make it harder to stay consistent Simple stressmanagement ideas: 510 minutes of deep breathing or meditation Gentle stretching or yoga Short outdoor walks Journaling or gratitude lists Therapy, coaching, or support groups when needed Choose strategies that feel doable and sustainable, not like another task. Prioritizing Sleep Sleep affects appetite, cravings, mood, and energy
Finding ways to manage stresswhether through exercise, meditation, or spending time with friendsis a vital part of the puzzle
Gastrointestinal symptoms such as nausea, vomiting, and diarrhoeareported by a significant proportion of patients, particularly during dose escalationcan lead to dehydration and nutritional changes
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Activation of GLP-1R by exendin-4 promoted the osteogenic differentiation, increased bone formation and osteoblast number and inhibited BMSC adipogenic differentiation, but wortmannin (PI3K inhibitor), and GLP-1R sh-RNA partially blocked the exendin-4-induced PI3K/AKT signaling activation and attenuated the facilitating effect of exendin-4 in BMSCs (Figure 1)
For constipation: psyllium husk This is the most common reason people add fiber on semaglutide, and the area with the clearest evidence
