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Soluble fiber from sources such as oats, legumes, flaxseeds, and psyllium can stimulate GLP-1 release from intestinal L-cells

Obesity-related low-grade inflammatory state can alter the pharmacokinetics of anti-TNF agents, leading to reduced drug concentrations and shorter half-life

Those using the full dose will benefit most from the treatment

doi:10.1016/j.trsl.2021.06.001