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First and foremost: dont stop your medication on your own

Nausea occurs in approximately 15-20% of patients and represents the most common side effect, typically emerging during dose escalation and often diminishing over several weeks as tolerance develops

Its non-selectivity, considered a clinical drawback, is a scientific advantage: it allows for the isolation of the relative contributions of each MCR subtype using selective antagonism protocols (HS024, JNJ-10229570, MCL-0129)

Use adequate contraception while taking this medication

Another naturally occurring sphingolipid, sphingosine-1-phosphate, has been shown in vitro to modulate the expression of GPX4 and FPN1, and TFRC, which may contribute to reduce radiation-induced ferroptosis in KGN cells (Zhao et al., 2023)

Given that GLP-1 medications reduce appetite, patients may struggle to meet protein requirements and should prioritise protein-rich foods at each meal