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In Ukraines Sumy region, bordering Russia, a large fire broke out after a Russian drone struck a civilian facility, Oleh Hryhorov, head of the regional military administration, said on Saturday

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These alterations may reflect underlying pathophysiological mechanisms of the disease [393, 441, 442]

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At this time it is unclear whether free radical involvement in Parkinson's disease is a primary or secondary event in nigral cell death or whether it occurs early or late in the disease process