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We emphasize that clinicians should adopt a holistic approachmonitoring growth and mental health, continuing nutrition and activity counseling, and obtaining family supportwhen prescribing these agents

84 Although these approaches show promise, they still need more validation for clinical use

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While GLP-1 receptor agonists like semaglutide and tirzepatide have revolutionised the field, ongoing research is exploring new targets and combination therapies to address the limitations of existing medications