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Factors increasing the production of reactive species can be internal, such as inflammation, or external such as pollution, UV exposure, xenobiotic compounds, and cigarette smoke

Acute acetaminophen intoxication induces direct neurotoxicity in rats manifested as astrogliosis and decreased dopaminergic markers in brain areas associated with locomotor regulation

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Why havent I heard more about glutathione

stress response) to 5-FOA, a control strain was constructed, designated pURA3-URA3 in the following context, which retained pTEF1-GSH1 but in which URA3 was under the control of its native promoter pURA3 ( Figure S1 C )

X is the reduced glutathione content