For weight loss, the main options are Wegovy (semaglutide), Saxenda (liraglutide), and Mounjaro (tirzepatide)
Remission of pre-diabetes to normal glucose tolerance in obese adults with high protein versus high carbohydrate diet: randomized controlled trial
Also, a small cross-sectional study of 36 women with PCOS noted no changes in depression scores associated with liraglutide use over 6 months 204 , while another reported worsening depressive symptoms, which correlated with higher perceived stress scores, in 43 exenatide users with diabetes and obesity against non-users at 3 months 205
Semaglutide: Single-Receptor Action Semaglutide is a GLP-1 receptor agonist
The activation of GIP receptors enhances insulin secretion and provides additional benefits for regulating appetite, type 2 diabetes, and weight loss
LPL is also a key player in the transport of fats to the cells that need the fat for fuel, particularly muscle cells