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Conversely, IR contributes to reduced dopamine transporter expression coupled with increased excitatory glutamatergic input, elevating extracellular dopamine levels

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Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice

The combination group experienced faster and greater repigmentation overall, with stronger differences reported on the face and upper extremities