Biological systems are not additive
Tirzepatide, with its dual action, may provide similar benefits
R This pathway is the primary defense against: Aflatoxin B1 (a carcinogenic mycotoxin produced by Aspergillus) Cadmium Epoxides (reactive Phase I intermediates from polycyclic aromatic hydrocarbons) Lipid peroxidation products (4-hydroxynonenal, malondialdehyde) Mercury (organic and inorganic forms) Reactive oxygen species (ROS) and reactive nitrogen species (RNS) GSTs exist in three locations: cytosolic (the largest class, with alpha, mu, pi, theta, sigma, omega, and zeta subfamilies), mitochondrial (kappa class), and microsomal (MAPEG family)
It could be expected that abrupt arousal may have led to enhanced breathing but as this did not appear to happen it is likely that GSHee interacted directly with the neural pathways/cellular mechanisms responsible for fentanyl-induced OIRD
Some say it boosts their libido, while others feel the opposite
namely, that we want more innovation that is valuable to patients, including those with rare disease
