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S-ALA: The two forms of alpha-lipoic acid Alpha-lipoic acid exists as two molecular mirror images, or isomers: R-ALA and S-ALA

Another potential explanation is altered hormones, though further research is needed to confirm the exact molecular mechanisms

Microglia, the primary immune responders in the brain, release proinflammatory cytokines when activated, which then stimulate nearby reactive astrocytes, amplifying local neuroinflammation

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