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Figure 6 Figure 7 3.3 NLRs and inflammasomes NLRs play crucial roles not only in sensing PAMPs and DAMPs but also in detecting disturbances in cellular homeostasis, such as redox imbalance, ion flux, and other forms of cellular stress ( in silico analyses increased, and these analyses identified more than 30 NLR family members ( With regard to function, most NLRPs are involved in immune and inflammatory responses by means of the assembly of a multiprotein platform known as the inflammasome ( Figure 8 )

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Those who are pregnant, breastfeeding, or have active cancer should avoid NAD+ therapy