Synucleinopathy is believed to be responsible for parkinsonism
All animal experiments were approved by the Institutional Animal Care and Use Committee of the College of Medicine at Gachon University (approval number: LCDI-2020-0135)
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The clinical imperative is clear: a shift from siloed, disease-specific management toward integrated, mechanism-based interventions that target the shared pillars of aging (37, 38, 47, 183)
Collectively, the data indicate that supplementation with EPA plus DHA blunts the pro-inflammatory NLRP3/IL-1beta response of human adipose tissue, providing a potential mechanism by which omega-3 fatty acid supplementation could mitigate diabetes risk in individuals with elevated apoB (Lamantia 2024
Inflammation 44 , 10491059 (2021)