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En el sistema nervioso central, el GLP-1 se encarga de regular el apetito y disminuir la absorcin intestinal por retraso del vaciamiento gstrico, actuando a nivel del hipotlamo y en el nervio vago, unindose a su receptor activando la sealizacin dependiente de las MAPK cinasas y modulando la actividad de los canales de Ca 2+ 22
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These findings provide a novel potential therapeutic target for CaOx kidney stones
If a patient takes a GLP-1 agonist, which slows gastric emptying and reduces caloric absorption, NAD+ precursor absorption may be further impairedmeaning the supplement dose might reach target tissue at lower-than-expected concentrations
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