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No BPC-157 and TB-500 are mechanistically unrelated

Biomaterials 279 , 121214 (2021)

3 In B12 deficiency, methylmalonic acid (MMA) can accumulate, and it is thought that elevated MMA, alongside elevated homocysteine, contributes to damage of the myelin sheath (which protects nerve cells and speeds up nerve transmission), which can cause irreversible neurological problems

Both drugs are being developed by Novo Nordisk, likely reflecting a portfolio strategy: CagriSema as the first-to-market injectable combination, and amycretin as a follow-on oral option for patients who prefer pills

Preoperative preparation is necessary as the intrathecal catheter may be replaced during surgery

The sulphate-free formula stops that tight, squeaky feeling