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Use scrubs on areas that accumulate rough skin, such as: Apply lotion immediately after showering when skin is a little bit damp

Moreover, various IRE1 inhibitors may have different off-target effects, depending on the experimental context

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Hoogeveen EK, Kostense PJ, Beks PJ, MacKaay AJC, Jakobs C, Bouter LM, Heine RJ, and Stehouwer CDA (1998)

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Effect of ginger on acute and delayed chemotherapy-induced nausea and vomiting: a pilot, randomized, open-label clinical trial