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for longerterm storage, freezing at approximately 20 C is recommended to preserve peptide integrity

Haley JE, Dickenson AH

Among other things, there is no guarantee that planned or ongoing studies will be completed as planned, that future study results will be consistent with study results to date, that orforglipron will prove to be a safe and effective treatment for obesity or overweight, that orforglipron will receive regulatory approval, or that Lilly will execute its strategy as expected

They also cited a study of more than 25,000 subjects that found a 3.5-fold increase in intestinal obstruction rates for people who took GLP-1 RA drugs

however, its functional role is not known

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