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Glutathione modulates this pathway in multiple ways: it can shift melanin production toward the lighter pheomelanin, it interacts with intermediate molecules in the melanin pathway, and it helps maintain redox balance that affects enzyme activity inside melanosomes

However, several studies [72, 73, 74, 75] have shown the significant role of Prx2 as an efficient H 2 O 2 scavenger in the erythrocyte antioxidant system