The studies on CBD and NAC are very interesting with the latter focusing on glutamate imbalance specifically
A quick search on the internet revealed clinics offering private treatments for people who have not necessarily been diagnosed as being vitamin B12 deficient: $30 for Five Week Wellness Package with Vitamin B6 and B12 Injections at Fit Medical Weight Loss ($150 Value) and a London based clinic offering Vita Boost injection injections of vitamins B12 in to the body, helping keep energy levels up as well as general well being
In terms of its effects, it appears to impact drinking in ways (though not necessarily mechanisms) similar to naltrexone (FDA-approved) and topiramate (prescribed off label for alcohol use disorder), which have a greater effect in reducing intensity of drinking on drinking days relative to their effects on whether someone drinks at all (i.e., abstinent days) although all of them do increase abstinent days to some degree on average)
Start your intake How Metformin and Semaglutide Work Together Metformin reduces glucose production in the liver and improves insulin sensitivity at the cellular level, while semaglutide signals satiety in the brain and slows gastric emptying
At the research peptide level, retatrutide and tirzepatide cost roughly the same ($150$500/month depending on dose)
Head-to-head diabetes trials put it ahead on both weight and blood sugar