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It may exist both with and without copper binding, with copper affinity appearing to play a role in biological signaling

The glutamate and cysteine residues are connected by a -amide bond, forming the structure of -glutamylcysteine

Effect of L-carnitine therapy on patients in maintenance hemodialysis: a systematic review and meta-analysis

Funding The authors are grateful to King Saud University, Riyadh, Saudi Arabia, for funding this work through the Ongoing Research Funding program - Research Chairs (ORF-RC-2025-5100)

However, the roles of other phenotypes, such as fibroblast-like and adipocyte-like phenotype, in vascular function and BP regulation remain to be further explored

nevertheless, their distinct N-terminal residuesglycine, alanine, or aspartic acidmay modestly affect stability and biological efficacy