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Because the majority of the -cells do not express GLP-1R, and also because GLP-1 inhibits glucagon secretion even in T1D patients with low insulin pancreatic reserve, the mechanism by which GLP-1 decreases glucagon secretion is still a matter of debate [15]
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Fat and dietary fiber (from carbohydrate-rich foods) also have this effect, which is why a balance of protein, fat, and carbohydrate is important
Factors That Determine How Long You'll Stay on GLP-1 Medications Your personal weight loss goals, starting body composition, and metabolic rate all influence treatment duration
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