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The mitochondrial membranes are rich in polyunsaturated fatty acids, making them highly susceptible to a specific type of oxidative damage known as lipid peroxidation

Cox, Daniel Eichner Published: Drug Testing and Analysis, Volume 7, Issue 1, January 2015, pages 3138 DOI: 10.1002/dta.1715 URL: AOD9604 was incubated in human serum and rat plasma at room temperature to study in vitro metabolic degradation

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While these studies confirm the existence of ferroptosis and oxidative accumulation, the specific and complex mechanism remains to be fully elucidated

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