The bond is formed from the COOH in the R group of glutamic acid, not the COOH.
Key takeaways Avoid grapefruit and grapefruit juice Avoid St Johns wort and certain herbal supplements Use caution with some antidepressants and other medicines Check before taking highdose supplements, including turmeric or curcumin capsules In this article How does tamoxifen work
Elife (2013) 2:e00947
Ming G feng, Li X, Yin J ye, Ai Y hang, Xu D miao, Ma X hua, et al
Mizera and Lieske have rooted their careers on a philosophy that goes beyond conventional care: combining the precision of modern medicine with evidence-based nutrition, exercise, sleep, and lifestyle optimization
each R 4 is independently selected from F, Cl, Br, I, CN, NO 2 , CF 3 , OR 9 , OCF 3 , NR 8 R 9 , C(O)R 10 , CO 2 R 9 , C(O)NR 8 R 9 , N(R 8 )C(O)R 10 , N(R 8 )CO 2 R 10 , NHS(O) 2 R 10 , S(O) 2 NR 8 R 9 , C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 1 -C 6 heteroalkyl, C 1 -C 6 haloalkyl, C 2 -C 7 heterocycloalkyl, C 6 -C 10 aryl, and C 3 -C 9 heteroaryl