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The loading phase builds antioxidant stores through frequent sessions over several weeks

While analogs with reduced IGFBP affinity show increased potency in vitro, careful pharmacokinetic work has shown that such analogs are actually cleared more rapidly than native IGF-1 after parenteral administration in vivo, because the binding proteins that inhibit activity also serve as a circulating reservoir that prolongs systemic presence

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10 L titer virus was added to the respective wells except control group

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