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For instance, melatonin has been demonstrated to inhibit MMP9 in a mouse model of cerebral ischemia (Tai et al., 2010)

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In group 4, NG-nitro-L-arginine (L-NNA) was applied intraperitoneally (20 mg/kg i.p.) alone or in the combination with PTX (10 mg/kg i.p.) prior to WRS