Long-term DSIP safety has not been established through clinical trials
Unlike hormones, which have broad systemic effects, peptides work on specific cellular receptors with targeted mechanisms
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Methods: A cohort of 41 patients (30 women, median age 68 10 years) admitted to Pisa University Hospital between January 1, 2020, and November 30, 2024, with atherosclerotic acute ischemic stroke (extracranial internal carotid artery) and treated with EVT and extracranial stent release was analyzed
Dudli S, Haschtmann D, Ferguson SJ
Treatment with cortagen resulted in a decrease in total antioxidant activity primarily in blood serum samples, as well as inhibition of antioxidant enzymes, glutathione peroxidase in the brain and SOD in blood serum