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Toxicol Pathol 35:495516 Vitale I, Pietrocola F, Guilbaud E et al (2023) Apoptotic cell death in diseasecurrent understanding of the NCCD 2023

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This is tricky because metabolic adaptation and plateau effects can cause similar symptoms

Overall, animal studies have shown beneficial effects of IGF-I in the treatment of various neuromuscular disorders, although the effects were more evident in the mild forms of the diseases