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Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases

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doi:10.1016/j.cofs.2016.02.002 [Elsevier] 116

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The APOE 4 allele, a significant genetic risk factor for sporadic AD, contributes to BBB dysfunction and exacerbates AD pathogenesis through the APOE4-CypA-MMP9 pathway