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If the answer is "no" then it sends the feedback up the chain, where GHRH gives it permission to secrete more hormone and get the job done

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High Chronic Stress: Elevated stress levels significantly increase the powerful hormone cortisol, which directly stimulates increased hunger and fat storage effectively

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(2025) Use of glucagon-like peptide-1 receptor agonists in idiopathic intracranial hypertension: a systematic review

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