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Western blot analysis revealed that recombinant CXCL10 treatment sharply increased the levels of COL1A1, p-JUN, and p-JNK in the CXCL10 group, whereas IL18R1 antibody treatment reversed their levels close to those of the control in the 10+18ab group (Fig

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Subcutaneous absorption varies by site

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Similarly, deferoxamine, the delivery of which via topical eye drops is limited by poor corneal permeability, fails to achieve effective concentrations in the optic nerve (158)