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Another possible cause is a disordered immune system

Hayes and Pulford, 1995

High-dose methotrexate-induced fulminant hepatic failure and pancytopenia in an acute lymphoblastic leukaemia paediatric patient

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Furthermore, in the absence of protease treatment, a distinct S2 band was detected using a Cleaved SARS-CoV-2 S protein (Ser686) antibody, confirming efficient cleavage at the S1/S2 site due to the presence of a furin cleavage site (Fig

Overall, these data strongly support that lapatinib exerts an inhibitory role on neuronal ferroptosis by blocking the downregulation of GPX4