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A 11.3c In patients with CKD who are at increased risk for CV events, use of a GLP-1 receptor agonist reduces renal end points, primarily albuminuria, progression of albuminuria, and CV events (Table 9.1)
Its molecular formula is C23H27ClO7 and the molecular weight is 450.91
J Med Chem 58(3):10201037
Additionally, they suppress glucagon secretion , slow gastric emptying, and promote satiety through central nervous system pathways, which collectively improve glycaemic control and facilitate weight loss
The effects of combination canagliflozin and glucagon-like peptide-1 receptor agonist therapy on intermediate markers of cardiovascular risk in the CANVAS program