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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Richie JP, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE

Even when fertilization is achieved, oxidative stress (inflammation)-induced apoptosis (cell death) may result in embryo fragmentation implantation failure insufficient luteal hormonal levels miscarriage impaired placenta development inadequate growth of the uterine lining (necessary for embryo development congenital abnormalities More reproductive condition-specific

Protection against reactive oxygen species by selenoproteins

Oxidative stress can occur as a result of increased metabolic rate, increased oxygen tension, compromise of normal cellular antioxidants and many others endogenous and exogenous factors (Figure 1)

However, cancer patients usually benefit from vitamin B12 supplementation