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Group 6 consists of 4 mice, as prior experiments showed acceptable variability

The main cause of CKD-induced anemia is reduced output of erythropoietina protein that stimulates red blood cell productionfrom the kidneys

Cohen's d = 1.06

Cancer Res 44 , 34033407 (1984)

Activation of the UPR generally serves as a readout for ER stress, but it is not clear what diminished ER stress implies in terms of an actual accumulation of unfolded proteins, particularly because some stressors, such as palmitate loading, activate the UPR apparently independent of the protein folding process (Volmer et al., 2013)

23 Increases in Itch/AIP4 levels and transcription in p53 wt Mel-29 cells and AIP5 in p53 mut Mel-23 cells suggested that the decrease in TAp73 was due to proteasomal degradation