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To validate these findings, we assessed glucose uptake rates through flow cytometric measurement of a fluorescently labelled glucose analogue (2-NBDG)

Nature Medicine, 21(1), 27-36

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Interestingly, many of these brain regions do not express Gipr or Glp1r 31,32 , suggesting that these are secondary downstream pathways that are activated indirectly by mGIPR-Ab/P3

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The net effect across all three pathways: reduced appetite, improved insulin sensitivity, better glucose regulation, increased energy expenditure, and reduced liver fat