Jump to: How Mounjaro affects the pancreas | The evidence on pancreatitis risk | Whats the actual risk | Mounjaro and pancreatitis in type 2 diabetes | Documented cases of pancreatitis | Warning signs to watch for | If you suspect pancreatitis | Who should be extra cautious | Comparing to other medications | Long-term considerations | Recovery from pancreatitis | How Second Nature supports safety | NHS guidance | Frequently asked questions | Take home message Mounjaro (tirzepatide) can cause pancreatitis, but this is a rare side effect occurring in only 0.32-0.39% of patients, similar to placebo rates in clinical trials
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Elbaset MA, Mohamed B, Moustafa PE, Mansour DF, Afifi SM, Esatbeyoglu T, Abdelrahman SSM, Fayed HM (2023) Erythropoietin suppresses the hepatic fibrosis caused by thioacetamide: role of the PI3K/Akt and TLR4 signaling pathways
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The American Heart Association and the Heart Failure Society of America note that GLP-1R agonists can decrease systemic inflammation and platelet aggregation, contributing to their cardiovascular benefits [101]