doi: 10.3389/fragi.2025.1691007 Received 22 August 2025 Revised 30 October 2025 Accepted 06 November 2025 Published 27 November 2025 Volume 6 - 2025 Edited by Kieran Reid, Harvard Medical School, United States Reviewed by Shannon Hernon, Harvard Medical School, United States Nicole Bajdek, Harvard Medical School, United States Updates Copyright 2025 Dinkla, Beavers, Robbins, Akpalu, Wherry, Miller, Beavers, Espinoza, Trejo, Stepanenko and Cortes
avoid direct sunlight Room Temperature Store in a cool, dry place away from direct sunlight
Day 1 reality I went into Day 1 with realistic expectations
It's effective on post-inflammatory hyperpigmentation from acne breakouts, sunspots from UV damage and even melasma
Certain foods can make it worse, like: Eating too quickly, skipping meals, or taking supplements can also add to the problem
The main clinical concern is that rapid weight loss may alter how much thyroid hormone your body needs, potentially requiring dose adjustments during the first months of treatment
