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Type 2 diabetes (though it's not yet approved for this use) : In the phase 3 ACHIEVE-1 trial, adults with early type 2 diabetes who took orforglipron experienced a drop in their A1C from 8% to 6.5%6.7% after 40 weeks

Metabolism naturally slows with age, and body composition shifts toward relatively less muscle and more fat unless we actively resist it

Approximately 2530% of patients experience some degree of nausea, while 1015% report vomiting or diarrhea

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Does it change anything about your biology

By contrast, Eli Lilly expects about 25 percent sales growth this year.