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In particular, androgens have direct effect on the growth plate in stimulating longitudinal growth, and estrogens (derived from androgen aromatization) lead to epiphysis fusion [35]

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HDACi exert their effects by inhibiting HDAC activity

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Over the past two decades, several studies have indicated that neuroinflammation is a critical reason for the onset, deterioration, relapse, and maintenance of depression ( Figure 2 ) (Kopschina Feltes et al., 2017

A study in Brain, Behavior, and Immunity showed that acute sleep deprivation significantly increased cortisol levels in a small sample of healthy adults