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Kopetz S , Yoshino T, Kim TW, Yaeger R, Desai J, Wasan HS, Cutsem EV, Maughan T, Eng C, Tie J, Elez E, Lonardi S, Zhang X, Chung C, Usari T, Nicholz T, Murphy DA, Tabernero J, Ciardiello F

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Acknowledgements We are thankful to the support of China Pharmaceutical University and all those who have assisted in improving the quality of this article

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